Science of Hyperbaric Oxygen Therapy in Traumatic Brain Injury

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The Science of HBOT in TBI

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Shi XY, Tang ZQ, Xiong B, Bao JX, Sun D, Zhang YQ, Yao Y. Cerebral perfusion SPECT imaging for assessment of the effect of hyperbaric oxygen therapy on patients with postbrain injury neural status. Chin J Traumatol. 2003 Dec;6(6):346-9. 39 Neubauer RA. The effect of hyperbaric oxygen in prolonged coma. Possible identification of marginally functioning brain zones. Minerva Med Subaecquea ed Iperbarica, 1985;5:75. 40 Shn-rong Z. Hyperbaric oxygen therapy for coma (a report of 336 cases). In: Procedures of the XIth International Congress on Hyperbaric Medicine, eds. Li W-ren, Cramer FS. Best Publishing Co, Flagstaff, AZ, 1995. p.279-285. 41 Neubauer RA. Severe natural gas poisoning successfully treated with hyperbaric oxygen – 2 years later. Neurotoxicology and Occupational Neurology, 1990;10. 42 Eltorai I, Montroy R. Hyperbaric oxygen therapy leading to recovery of a 6-week comatose patient afflicted by anoxic encephalopathy and posttraumatic edema. J Hyperbaric Med, 1991;6: 189-198. 43 Neubauer RA. Severe natural gas poisoning successfully treated with hyperbaric oxygen – 2 years later. Neurotoxicology and Occupational Neurology, 1990;10; Harch PG, Van Meter KW, Gottlieb SF, Staab P. HMPAO SPECT brain imaging of acute CO poisoning and delayed neuropsychological sequelae (DNSS). Undersea & Hyperbaric Medicine, 1994; 21 (Suppl): 15. 44 Neubauer RA, Gottlieb SF, Miale A, Jr. Identification of hypometabolic areas in the brain using brain imaging and hyperbaric oxygen. Clin Nucl Med 1992;17(6):477-81. 45 Harch PG, Neubauer RA (1999) Hyperbaric oxygen therapy in global cerebral ischemia/ anoxia and coma. In Jain KK (ed) Textbook of Hyperbaric Medicine, 3rd Revised Edition, Chapter 18. Hogrefe & Huber Publishers, Seattle WA 1999: 319-345. 46 Neubauer RA, James P. Cerebral oxygenation and the recoverable brain. Neurol Res, 1998;20(Suppl 1): S33-S36. 47 Harch PG, Van Meter KW, Gottlieb SF, Staab P. HMPAO SPECT brain imaging and HBOT 1.5 in the diagnosis and treatment of chronic traumatic, ischemic, hypoxic and anoxic encephalopathies. Undersea and Hyperbaric Medicine, 1994;21(Suppl):30. Neubauer RA, James P. Cerebral oxygenation and the recoverable brain. Neurol Res, 1998;20(Suppl 1): S33-S36. 48 Harch PG, Van Meter KW, Gottlieb SF, Staab P. HMPAO SPECT brain imaging and HBOT 1.5 in the diagnosis and treatment of chronic traumatic, ischemic, hypoxic and anoxic encephalopathies. Undersea and Hyperbaric Medicine, 1994;21(Suppl):30. 49 Golden ZL, Neubauer R, Golden CJ, Greene L, Marsh J, Mleko A Improvement in cerebral metabolism in chronic brain injury after hyperbaric oxygen therapy. Intern. J. Neuroscience 2002;112:119-131. 50 Heyman A, Saltzman HA, Whalen RE. The use of hyperbaric oxygenation in the treatment of cerebral ischemia and infarction. Circulation. 1966 May;33(5 Suppl):II20-7. 51 Neubauer RA, End E. Hyperbaric Oxygenation as an Adjunct Therapy in Strokes Due to Thrombosis. Stroke, 1980;11(3):297-300; Jain KK. The Role of Hyperbaric Oxygenation in the Management of Stroke. In Jain KK (ed) Textbook of Hyperbaric Medicine, 2nd Edition; Hogrefe & Huber, Bern, 1996;17: 253-273. 52 Isakov IuV, Pravdenkova SV. [Respiratory and central hemodynamic responses during a session of hyperbaric oxygenation in patients with acute cerebral circulatory disorders]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1981;81(8):1158-62. Russian. 53 Anderson DC, Bottini AG, Jagiella WM, Westphal B, Ford S, Rockswold GL,Loewenson RB. A pilot study of hyperbaric oxygen in the treatment of human stroke. Stroke. 1991 Sep;22(9):113742. 54 Kanno T, Nagata J, Nonomura K, Asai T, Inoue T, Nakagawa T, Mitsuyama F. New approaches in the treatment of hypertensive intracerebral hemorrhage. Stroke. 1993 Dec;24(12 Suppl):I96-100; discussion I107-8. 55 Lim J, Lim WK, Yeo TT, Sitoh YY, Low E. Management of haemorrhagic stroke with hyperbaric oxygen therapy--a case report. Singapore Med J. 2001 May;42(5):220-3. 56 Rusyniak DE, Kirk MA, May JD, Kao LW, Brizendine EJ, Welch JL, Cordell WH, Alonso RJ; Hyperbaric Oxygen in Acute Ischemic Stroke Trial Pilot Study. Hyperbaric oxygen therapy in


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