Science of Hyperbaric Oxygen Therapy in Traumatic Brain Injury

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The Science of HBOT in TBI

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with hyperbaric oxygen following lateral fluid-percussion injury. J Neurosurg. 2007 Apr;106(4):687-94. 22 Rossignol DA, Rossignol LW, James SJ, Melnyk S, Mumper E. The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study. BMC Pediatr. 2007 Nov 16;7:36. 23 Rink C op. cit. 24 Liu ZJ, Velazquez OC. Hyperoxia, endothelial progenitor cell mobilization, and diabetic wound healing. Antioxid Redox Signal. 2008 Nov;10(11):1869-82. 25 Wang XL, Yang YJ, Xie M, Yu XH, Wang QH. [Hyperbaric oxygen promotes the migration and differentiation of endogenous neural stem cells in neonatal rats with hypoxicischemic brain damage]. Zhongguo Dang Dai Er Ke Za Zhi. 2009 Sep;11(9):749-52. Chinese. 26 Chen J, Chen YH. [Effects of hyperbaric oxygen on synaptic ultrastructure and synaptophysin expression in hippocampus of neonatal rats with hypoxic-ischemic brain damage.]. Zhonghua Er Ke Za Zhi. 2010 Mar;48(3):199-203. Chinese. 27 Yamashita S, Hirata T, Mizukami Y, Cui YJ, Fukuda S, Ishida K, Matsumoto M, Sakabe T. Repeated preconditioning with hyperbaric oxygen induces neuroprotection against forebrain ischemia via suppression of p38 mitogen activated protein kinase. Brain Res. 2009 Dec 8;1301:171-9. Epub 2009 Sep 9. 28 Wang QH, Yang YJ, Chen CF, Yao Y, Li M. [Protective effects of delayed multiple course hyperbaric oxygen treatment against hypoxic-ischemic brain damage in neonatal rats]. Zhongguo Dang Dai Er Ke Za Zhi. 2009 Jun;11(6):464-70. Chinese. 29 Chen J, Chen YH. [Effects of hyperbaric oxygen on intrauterine hypoxic-ischemic brain damage in neonatal rats]. Zhongguo Dang Dai Er Ke Za Zhi. 2009 May;11(5):380-3. Chinese. 30 Tinianow CL, Tinianow TK, Wilcox M. Effects of hyperbaric oxygen on focal brain contusions. Biomed Sci Instrum. 2000;36:275-81. 31 Harch PG, Kriedt CL, Weisand MP, Van Meter KW, Sutherland RJ. Low pressure hyperbaric oxygen therapy (HBOT 1.5) induces cerebrovascular changes and improves cognitive function in a rat traumatic brain injury (TBI) model. Undersea Hyper Med 2001; 28 Suppl :28. 32 U.S. Navy Diving Manual, Volume 1. NAVSEA 0994-LP-001-9010, Revision 1, 1 June 1985. Sec. 2.4.6.1, p2-20. Best Publishing Co., Flagstaff, AZ; Moon RE, Gorman DF. Treatment of the Decompression Disorders, Chapter 18. In: The Physiology and Medicine of Diving, 4th Edition, eds. Bennett P, Elliott D. W. B. Saunders Company, Ltd. London, 1993. 33 Harch PG, Gottlieb SF, Van Meter KW, Staab P. SPECT brain imaging in the diagnosis and treatment of type II decompression sickness. Undersea Hyper Med, 1992;19(Suppl):42. Harch PG. Late treatment of decompression illness and use of SPECT brain imaging. In: Moon RE, Sheffield PE, editors. Treatment of decompression illness. 45th Workshop of the Undersea and Hyperbaric Medical Society. Kensington (MD) UHMS, 1995, 203-42; Barratt DM, Harch PG, Van Meter K. Decompression illness in divers: A review of the literature. Neurologist 2002; 8:186202. 34 Harch PG, Van Meter KW, Gottlieb SF, Staab P. 29. Harch PG, et al. Delayed treatment of type II DCS: the importance of HBOT 1.5 and HMPAO SPECT brain imaging in its diagnosis and treatment. Undersea Hyper Med, 1993;20(Suppl):51 35 Harch PG, Van Meter KW, Gottlieb SF, Staab P. The effect of HBOT tailing treatment on neurological residual and SPECT brain images in type II (cerebral) DCI/CAGE. Undersea and Hyper Med, 1994;21(Suppl):22-23. 36 Harch PG. Late treatment of decompression illness and use of SPECT brain imaging. In: Moon RE, Sheffield PE, editors. Treatment of decompression illness. 45th Workshop of the Undersea and Hyperbaric Medical Society. Kensington (MD) UHMS, 1995, 203-42; Barratt DM, Harch PG, Van Meter K. Decompression illness in divers: A review of the literature. Neurologist 2002; 8:186202. 37 Harch PG. Late treatment of decompression illness and use of SPECT brain imaging. In: Moon RE, Sheffield PE, editors. Treatment of decompression illness. 45th Workshop of the Undersea and Hyperbaric Medical Society. Kensington (MD) UHMS, 1995, 203-42.


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