Life Sciences

Cambridge, MA – Dacon Corporation has completed construction on Vedanta Biosciences’ new facility designed by DiMella Shaffer.

A clinical-stage biopharmaceutical company developing oral therapies based on defned bacterial consortia, Vedanta’s drug candidates use human commensal bacteria to treat diseases associated with the disruption of the human gut microbiome. The new facility houses endto-end CGMP manufacturing capabilities for multiple drug candidates from clinical development to commercial launch in a manner that is compliant with global regulatory standards.

Founded in 2010, Vedanta was one of the frst life sciences frms to manufacture CGMP-grade defned bacterial consortia in powdered form. Today it has completed over 200 successful CGMP runs and advanced fve drug candidates into the clinic. Currently it is planning a Phase 3 study for its lead candidate VE303 in high risk Clostridioides diffcile infection (CDI).

“We believe that taking a targeted approach to modulation of the human microbiota, using rigorously controlled and defned pharmaceutical-grade

edanta iosciences compositions, will be instrumental to the evolution of microbiome-based therapies into a reliable new drug modality for patients across a range of indications,” said Bernat Olle, Ph.D., CEO of Vedanta Biosciences. “This facility, combined with the expertise and talent of our team, is designed to manufacture our microbiome product candidates as standardized compositions with consistent quality attributes at a large scale.” Comments Kevin Quinn, Dacon’s CEO, “Vedanta’s work is both pioneering and fascinating. Their excitement is tangible onsite, with promising results from clinical studies that are invoking hope for those suffering from serious diseases.”

Burlington, MA – STEM Solutions, LLC recently completed work on ProtaGene’s new lab at the new Burlington Bio Center, located at 4 Burlington Woods in Burlington. ProtaGene is a CRO partner for the cell and gene therapy and

rotaGene lab

biopharmaceutical industries.

“STEM was a pleasure to work with on this project,” said Steve Cooke, senior project manager for PIDC Construction, the general contracting frm heading up the renovation of the center and lab build out. “STEM Solutions provided and installed fume hoods, stainless steel sink bases, painted steel casework, electrical ceiling panels, epoxy counters, cylinder racks, and gas plumbing.”

The lab was designed by Jacobs, who focused on taking advantage of the building’s natural light sources and natural setting to complete the space.

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• Building strong relationships based on honesty and experience

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